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Oligomer length defines the self-assembly of single-stranded DNA–collagen complex fibers

James, B. D., Saenz, S., Van Gent, A., & Allen, J. B. (2019). Oligomer length defines The Self-Assembly OF Single-Stranded DNA–COLLAGEN Complex Fibers. ACS Biomaterials Science & Engineering, 6(1), 213-218. doi:10.1021/acsbiomaterials.9b01435

https://doi.org/10.1021/acsbiomaterials.9b01435

Abstract: Collagen and single-stranded DNA (ssDNA) complex to self-assemble into fibers depending on the length of the ssDNA and the relative amounts of collagen and ssDNA in solution. We report for the first time that when monodisperse, random sequences of ssDNA... Read More

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News and Views September 2020

News and Views September 2020. Regen. Eng. Transl. Med. 6, 361–363 (2020). https://doi.org/10.1007/s40883-020-00169-9

https://doi.org/10.1007/s40883-020-00169-9

Abstract: The American Institute for Medical and Biological Engineering (AIMBE) inducted its 2020 Fellows in an online ceremony on June 5. AIMBE is the authoritative voice and advocate for the value of medical and biological engineering to society. Its mission is... Read More

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Multi-dimensional elastic light scattering

Backman, V., Roy, H., Wali, R., Kim, Y., Liu, Y., Ameer, G., Yang, J., Webb, A., & Allen, J. (2006). U.S. Patent No. US 2006O155178A1. Washington, DC: U.S. Patent and Trademark Office.

https://patentimages.storage.googleapis.com/d1/d7/b6/22fb85c9917bb2/US20060155178A1.pdf

Abstract: A method of examining a sample includes measuring, as function of wavelength of light elastically scattered from the sample, at least 2 properties, selected from the group consisting of scattering angle theta of the light, Scattering angle phi of the... Read More

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Modulating expanded polytetrafluoroethylene vascular graft host response via citric acid‐based biodegradable elastomers

Yang, J., Motlagh, D., Allen, J., Webb, A., Kibbe, M., Aalami, O., . . . Ameer, G. (2006). Modulating expanded polytetrafluoroethylene vascular graft host response via citric acid-based biodegradable elastomers. Advanced Materials, 18(12), 1493-1498. doi:10.1002/adma.200600230

https://doi.org/10.1002/adma.200600230

Abstract: A biodegradable polyester elastomer, poly (1, 8‐octanediol citrate)(POC), is used to modify the lumen of expanded polytetrafluoroethylene (ePTFE) grafts via a spin‐shearing method followed by interfacial in situ polycondensation. We demonstrate successful surface modification of ePTFE grafts without affecting graft... Read More

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Mechanical and degradation property improvement in a biocompatible Mg-Ca-Sr alloy by thermomechanical processing

Henderson, H. B., Ramaswamy, V., Wilson-Heid, A. E., Kesler, M. S., Allen, J. B., & Manuel, M. V. (2018). Mechanical and degradation property improvement in a biocompatible Mg-Ca-Sr alloy by thermomechanical processing. Journal of the Mechanical Behavior of Biomedical Materials, 80, 285-292. doi:https://doi.org/10.1016/j.jmbbm.2018.02.001

https://doi.org/10.1016/j.jmbbm.2018.02.001

Abstract: Magnesium-based alloys have attracted interest as a potential material to comprise biomedical implants that are simultaneously high-strength and temporary, able to provide stabilization before degrading safely and able to be excreted by the human body. Many alloy systems have been... Read More

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Magnetic particle conjugates and methods of activating cell signaling

Allen, J., & Dobson, J. P. (2020). U.S. Patent No. US010765881B2. Washington, DC: U.S. Patent and Trademark Office.

https://patentimages.storage.googleapis.com/c3/fb/32/ee7ecff4eed13e/US10765881.pdf

Abstract: Embodiments of the present disclosure provide for magnetic particle conjugates, methods of making the magnetic particle conjugates, methods of using magnetic particle conjugates, and the like. Read More

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Magnetic particle conjugates and methods of activating cell signaling

Allen, J., & Dobson, J. P. (2020). U.S. Patent No. US 20200353276A1. Washington, DC: U.S. Patent and Trademark Office.

https://patentimages.storage.googleapis.com/9a/30/44/a754bf59a69cfd/US20200353276A1.pdf

Abstract: Embodiments of the present disclosure provide for magnetic particle conjugates, methods of making the magnetic particle conjugates, methods of using magnetic particle conjugates, and the like. Read More

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Light-scattering fingerprinting for characterization of smooth-muscle cell proliferation

Yang Liu, Josephine Allen, Young L. Kim, Vladimir Turzhitsky, Guillermo Ameer, and Vadim Backman "Light-scattering fingerprinting for characterization of smooth-muscle cell proliferation", Proc. SPIE 5319, Laser Interaction with Tissue and Cells XV, (1 July 2004); https://doi.org/10.1117/12.529175

https://doi.org/10.1117/12.529175

Abstract: Accelerated proliferation of smooth muscle cells (SMC) is known to play an integral role in atherosclerotic lesion formation. Thus, there has been significant interest in defining both positive and negative regulators of SMC growth. We have applied a novel optical... Read More

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Let’s Talk About Sex—Biological Sex Is Underreported in Biomaterial Studies

James, B. D., Guerin, P., & Allen, J. B. (2020). Let's talk about sex—biological sex is underreported in biomaterial studies. Advanced Healthcare Materials, 10(1), 2001034. doi:10.1002/adhm.202001034

https://doi.org/10.1002/adhm.202001034

Abstract: Precision medicine aims to better individualize healthcare. It requires that biomaterials be designed for the physiological characteristics of a specific patient. To make this a reality, biomaterials research and development must address differences of biological sex. More specifically, biomaterials should... Read More

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In vitro and in vivo biocompatibility assessment of free radical scavenging nanocomposite scaffolds for bone tissue regeneration

Dulany, K., Hepburn, K., Goins, A., & Allen, J. B. (2020). In vitro and in vivo biocompatibility assessment of free radical scavenging nanocomposite scaffolds for bone tissue regeneration. Journal of biomedical materials research. Part A, 108(2), 301–315. https://doi.org/10.1002/jbm.a.36816

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700846/

Abstract: Bone is the second most transplanted tissue in the world, resulting in increased demand for bone grafts leading to the fabrication of synthetic scaffold grafting alternatives. Fracture sites are under increased oxidative stress after injuries, affecting osteoblast function and hindering... Read More

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